autoimmune-Infectious-disease-elisa

EUROIMMUN ELISA

Key Facts
  • World’s largest manufacturer of autoimmune and infectious disease ELISA Kits.
  • The most comprehensive range of autoimmune and infectious Diseases ELISA Kits – More than 100 different kits.
  • All kits incorporate identical protocol (75 minutes) – Ease of automation.
  • All kits (IgG and IgM) protocols use common substrate and wash.
  • Conjugates are colour-coded
  • 2nd calibrator can be used as “cut off” calibrator – Savings for the lab.
  • All IgM kits contain IgG/RF absorbent. Eliminates interference from IgG and RF.
Routine diagnostics assays viz. ANA Screen, dsDNA NCX, SLE Profile and Individual ANA Antigens.
Rheumatology Markers viz. Cyclic Citrullinated Peptide (Anti CCP), Anti Sa and Rheumatoid Factor (IgG, IgM).
Phospholipids viz. Anti Cardiolipin, Beta-2 Glycoprotein, Phosphatidyl Serine etc.
Vasculitis & IBD Markers viz. ANCA (MPO, PR3 hn-hr) ANCA Profile, Saccharomyces cerevisiae etc.
Autoimmune Hepatitis Markers viz. LKM, AMA – M2, SLA / LP, LC – 1, etc.
Gluten-Sensitive Enteropathy (GSE) Markers viz. Tissue Transglutaminase and Gliadin.
Dermatology Parameters – ELISAs for detecting skin structural proteins (BP180, BP230, Desmoglein 1, Desmoglein 3, Envoplakin, Collagen type VII).
Thyroid Markers viz. TSH Receptor Antibodies, Thyroid peroxidase and Thyroglobulin.
Diabetology Markers viz. Glutamic Acid Decarboxylase (GAD) and Tyrosine phosphatase (IA2).
Alzheimer markers: β Amyloid (1-40),β Amyloid (1-42).total tau.
Acetylcholine receptors for the detection of Myasthenia Gravis.
Serum IgG & IgM Kits for ToRCH, Measles, Mumps, VZV, Dengue, EBV, SARS, C. Trachomatis, C. Pneumoniae, Mycoplasma pneumoniae, H.pylori, Diphtheria, Tetanus Toxoid, Borrelia, etc.
Avidity Kits for Toxoplasma gondii, CMV, Rubella, VZV, West Nile Virus and EBV – CA
CSF Diagnostics Kits for Toxoplasma gondii, HSV – 1, HSV – 2, CMV, Rubella, Measles, Mumps, VZV, TBE and EBV – CA
Range of Autoimmune & Infectious Products
  • dsDNA NCX
  • Test system for in vitro determination of antibodies against dsDNA in human serum or plasma for diagnosis of Systemic Lupus Erythematosus (SLE).
    Highly purified Neucleosomes as the new linking substance. it provides strong adhesive ability, even the smallest concentration of dsDNA is detected.
    Sensitivity 60%; i.e 8% more than RIA & 18% more than conventional ELISA
    Specificity- 98%
  • Anti CCP
  • Test system for the invitro determination of antibodies against CCP in human serum or plasma for the diagnosis of Rheumatoid Arthritis
    Highly specific (>98%)
    Sensitivity is nearly 80%.
    Helps in early diagnosis of RA.
    Aids in the prognosis for the further course of RA.
    Reliable results due to original CCP2 antigen.
    Breakable wells, automation possible.
  • ANCA
  • The ELISA test kit provides a semiquantitative in vitro assay for human autoantibodies of the immunoglobulin class IgG against six different antigens
    EUROIMMUN ANCA Elisa is 14% higher sensitive than the connventional Capture ELISA
    Calibrators are ready for use.
    The ELISA shows no cross reactivity.
    Antigen used in this ELISA are all native proteins purified from human neutrophils.
  • MPO
  • The ELISA test kit provides a quantitative assay for human autoantibodies of the IgG class against myeloperoxidase (MPO) in serum or plasma.
    ELISA shows no cross-reactivity.
    Very high specificity & sensitivity
    Most of ready to use reagents, breakable well even for small load
  • PR3 hn-hr
  • The ELISA test kit provides a semiquantitative or quantitative in vitro assay for human autoantibodies of the immunoglobulin class IgG against proteinase 3 (PR3) in serum or plasma for the diagnosis of granulomatosis with polyangiitis (Wegener’s) (GPA).
    High specificity and sensitivity with 99% and 94% respectively.
    Test performance is so far superior when compared to other conventional Elisa, even comparable with IFA
    Ready to use reagents with the exception of wash buffer.
  • ANCA Profile ELISA
  • Highly sensitive monospecific immunoassay
    The ELISA encompasses PR3, Lactoferrin, MPO, Elastase, Cathepsin G and BPI
    Quantification of autoantibody concentration
  • APS
  • ELISAs for the detection of antibodies against anti-cardiolipin, beta-2 glycoprotein, and phosphatidylserine.
    The immunoglobulin classes IgA, IgG, and IgM can be investigated separately or together (IgAGM).
    Highly specific- also in different control panels.
    High sensitivity in accordance with antibody prevalences frominternational meta-studies.
    Individual availability of all IgG classes recommended by the international consensus statement.
    Reliable and can be full automated using the EUROIMMUN Analyzer I or I-2P.
  • tTg
  • Test system for invitro determination of antibodies against Tissue Transglutaminase in Human serum or plasma for the diagnosis of gluten sensitive enteropathy and Duhring's dermatitis herpetiformis.
    Highly Sensitive, 96%
    High Specificity: 99%.
    No occurence of cross-reactivity.
    Ready to use reagents with the exception of wash buffer.
  • β Amyloid
  • High specificity and sensitivity with 77% and 78% respectively.
    Lyophilised calibrator series- for comfort and precision.
    No matrix effect- for excellent reproducibility.
    CE certification- optimal for accredited laboratories.
  • Total Tau
  • It provides a quantitative in vitro determination of total tau in patient CSF for the diagnosis of neuronal apoptosis.
    The functional sensitivity defined as the lowest concentration of a real sample with a CV <20% was found to be 85 pg/ml.
    Breakable wells for even lower sample load
  • Acetyl Choline receptor
  • The ELISA test kit provides a quantitative in vitro assay for human antibodies of the immunoglobulin class IgG against acetylcholine receptors in serum or plasma to support the diagnosis of Myasthenia gravis.
    No cross-reactions with other autoantibodies.
    Recombinant human foetal and adult acetylcholine receptors from HEK cells are used as the antigen.
    With high sensitivity and specificity.
    Ready to use reagents with exception of wash buffer.
  • TSH Receptor, TPO, thyroglobulin (TG)
  • During an autoimmune process, antibodies against one or several of the three autoantigens, thyroid peroxidase (TPO) and TSH receptor (TR), are most prevalent.
    Highly sensitive nad specific kit with a sensitivity of 89%, and a specificity of 100%
    Confirmation of Grave's disease with a prevalence of 90-100%.
    Most of the reagents are ready for use, hence user friendly
  • ToRCH
  • For the sensitive and specific determination having all the ToRCH parameters available separately
    Simple and fast test performance, can be automatable with EUROIMMUN automated elisa processors
    Ready to use reagents except wash buffer, universal color coded reagents can be exchange with any other elisa kits.
    Breakable wells for even very small sample load
    Class of IgG, IgM separately available
  • Measles
  • The ELISA test kit provides a quantitative in vitro assay for human antibodies of the IgG class against measles virus in cerebrospinal fluid (CSF).
    Use of measles virus lysates for sensitive detection of specific antibodies
    Calibrated with respect to the 3rd International Standard serum NIBSC 97/648.
    Fully automated processing and evaluation.
    High specificity.
  • Mumps
  • The ELISA test kit provides a quantitative in vitro assay for human antibodies of the IgG class against Mumps virus in cerebrospinal fluid (CSF).
    Semiquantitaive or quantitative determination of IgG antibodies against Mumps virus.
    High sensitivity and specificity.
    Fully automated processing and evaluation.
    No cross-reactivity.
  • VZV
  • Test system for the in vitro determination of antibodies against Varicella Zoster Virus in human serum or plasma.
    Test performance using fully automated analysis devices.
    High quality of the antigen used ensures a high sensitivity and specificity of the ELISA.
    No cross-reactivity.
    Breakable wells and can be perform in automated elisa processor
  • EBV
  • Highly specific and sensitive test for the detection of Epstein-Barr Virus antibodies.
    Aditional marker for acute infection.
    Fully automated processing of EUROIMMUN ELISA.
    Recombinant antigens are used for early and late stage of disease
    Ready to use reagents with the exception of wash buffer.
  • Anti SARS-CoV-2 ELISA
  • High Specificity of 99.6% due to the use of the spike protein domain S1, including the immunologically relevant RBD
    Separate immunoglobulin class available (IgG, IgM, IgA)
  • Anti-SARS-CoV-2 QuantiVac ELISA
  • Quantitative determination of Anti-SARS-CoV-2 S1/RBD antibodies.
    Excellent correlation with neutralisation test.
    Supports the detection and assessment of the immune response or vaccination.