autoimmune-Infectious-diseases-euroline

Autoimmune & Infectious LIA – EUROLINE

Key Facts
  • Separate membrane strip for each sample.
  • Total time for the assay is less than 110 minutes.
  • Highly pure antigens: No cross-reaction.
  • Easy and reliable differentiation between positive and negative samples.
  • Intensity of the antigen bands correlate with the antibody titer.
  • Availability of EUROLINE Scan to scan, read, interpret and store the results.
Autoantibody Profiles:
  • ANA Profile 1 (12 antigens).
  • ANA Profile 3 (15 Antigens).
  • Systemic Sclerosis Profile
    The EUROLINE ANA Profile 3 (IgG) for the detection of antibodies against 15 different nuclear, cytoplasmic and mitochondrial antigens.
    A multiplex approach for the determination of these antibodies in a single reaction.
    15 different antigens are nRNP, Sm, SS-A, Ro-52, SS-B, Scl-70, PM-Scl, Jo-1, CENP B, PCNA, dsDNA, nucleosomes, histones, ribosomal P-protein and AMA-M2, in serum or plasma.
    High Sensitivity & Specificity
    Multiplex approach for confirmation and differentiation of Nucleolar and Cytoplasamic ANA Patterns.
    Fully automatable with PlexMAT series and EUROBlotOne
  • ANA Profile 31 (with Mi2 & Ku).
  • Systemic Sclerosis Profile
    The EUROLINE ANA Profile et Mi-2 et Ku for the detection of antibodies against 17 different nuclear and cytoplasmic and mitochondrial antigens
    17 different antigens are Mi-2, Ku, nRNPSm, Sm, SS-A (native), Ro-52, SS-B, Scl-70, PM-Scl100, Jo-1, CENP B, PCNA, dsDNA, nucleosomes, histones, ribosomal P-protein and AMA M2 in serum or plasma
    High Sensitivity & Specificity
    Multiplex approach for confirmation and differentiation of Nucleolar and Cytoplasamic ANA Patterns.
    Fully automatable with PlexMAT series and EUROBlotOne
  • ANA profile 33.
  • ANA Profile 3 plus DFS.
  • Systemic Sclerosis Profile
    The EUROLINE “ANA Profile 3 plus DFS70 (IgG)” for the detection of antibodies against 16 different nuclear, cytoplasmic and mitochondrial antigens
    16 different antigens nRNP, Sm, SS-A, Ro-52, SS-B, Scl-70, PM-Scl, Jo-1, CENP B, PCNA, dsDNA, nucleosomes, histones, ribosomal P-protein, AMA M2 and DFS70 in serum or plasma
    High Sensitivity & Specificity
    Multiplex approach for confirmation and differentiation of Nucleolar and Cytoplasamic ANA Patterns.
    Fully automatable with PlexMAT series and EUROBlotOne
  • Cytoplasmic profile
  • Systemic Sclerosis Profile
    The EUROLINE test kit provides qualitative in vitro determination of human autoantibodies of the immunoglobulin class IgG to 10 different antigens AMA-M2, M2-3E, rib. P-protein, Jo-1, SRP, PL-7, PL-12, EJ, OJ and Ro-52 in serum or plasma
    Easy diagnosis of primary biliary cholangitis, systemic lupus erythematosus (SLE) and poly-/dermatomyositis.
    multiplex approach for the detection of 10 autoantibodies that cause some of the cytoplasmic patterns described in the consensus, in one incubation.
    High Sensitivity & Specificity
    Multiplex approach for confirmation and differentiation of Cytoplasamic ANA Patterns.
    Fully automatable with PlexMAT series and EUROBlotOne
  • Myositis Profile.
  • Systemic Sclerosis Profile.
  • Systemic Sclerosis Profile
    EUROLINE Systemic sclerosis (Nucleoli) profile (IgG)
    Exclusively designed to detect 13 different Systemic Sclerosis specific antibodies and Anti Ro-52 in parallel.
    First membrane-based test system to offer such a comprehensive spectrum of systemic sclerosis-associated antigens Scl-70, CENP A, CENP B, RP11 and RP155 (RNA Polymerase III subunits), fibrillarin, NOR90, Th/To, PM-Scl100, PM-Scl75, Ku, PDGFR (platelet-derived growth factor receptor) and Ro-52 in serum or plasma to support the diagnosis of progressive systemic sclerosis (SSc, diffuse and limited form) and overlap syndromes.
    High Specificity 98-100%
    High Sensitivity in SSc Patients >85%
    Multiplex approach for confirmation and differentiation of Nucleolar ANA Patterns.
    Fully automatable with PlexMAT series and EUROBlotOne
  • ANCA Profile.
  • Liver Profile.
  • Ganglioside Profile.
Infectious Disease Profiles:
  • ToRCH Profile
  • EBV Profile
  • Borrelia Profile
  • Hantavirus Profile
  • Parvovirus B19 Profile