Calprotectin is the best marker to discriminate between organic (IBD) and non-organic bowel disease (IBS). Calprotectin is a reliable indicator of inflammation in several pathologies. Patients suffering from IBS do not have increased faecal calprotectin values. Faecal calprotectin concentrations, as measured by the BÜHLMANN Calprotectin assays, are significantly elevated in patients with IBD and correlate well with endoscopic and histological assessment of disease activity.
CICs are detectable in a variety of systemic disorders. They provide useful, clinical information regarding immunopathology, prognosis and follow-up of rheumatic and autoimmune disorders. BÜHLMANN Labs offers a well-established and widely used assay that provides sensitive results within 2 hours.
Measurement of anti-C1q auto antibodies in patients with Systemic Lupus Erythematosus (SLE) allows for determination of the risk of development of active lupus nephritis. The BÜHLMANN anti-C1q auto antibody ELISA can be used as an inexpensive and technically simple way to exclude the risk of renal flair in the months following the test with a sensitivity of 95%. In the case of active lupus nephritis, consecutive determination of anti-C1q antibodies is a tool to evaluate the efficacy of immunosuppressant treatment.